New Catalyst Carrier for Flow Synthesis

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What are synthesis-based heterogeneous metal catalysts?

Synthesis-based heterogeneous metal catalysts use DualPore™ (reference: “Material Strengths”) as a catalyst solid support. The product is highly active, has low back pressure, and is suitable for mass production flow synthesis, especially for continuous flow chemical processes and synthesis (or flow precision synthesis technology, continuous flow chemistry, continuous flow process).

New Catalyst Carrier for Flow Synthesis

Flow synthesis technology aims to complete a synthesis reaction by passing raw materials through a catalyst-packed column. Because of its various advantages in terms of environmental load reduction, efficiency, and safety, it is used by many large oil plants.

However, due to the lack of suitable catalyst support for heterogeneous catalysts, compounds such as pharmaceuticals and fine chemicals that require complex synthetic reactions rarely undergo flow synthesis technology.

DualPore™’s catalyst carrier has nanoscale (10-9m) “pores” and microscale (10-6m) “through-holes” not found in conventional particles. This two-stage structure makes for a high performing low-back pressure catalyst column, allowing substances including synthetic raw materials to rapidly diffuse into every corner of the particles. The perfusion effect is achieved through efficient contact with the catalyst and separation improvement, supported by our proprietary technology on the surface of DualPore™ particles.

This will pave the way for mass-production flow synthesis that makes the most of flow synthesis technology without the restrictions of equipment installation locations due to high-pressure gas regulations.

Compared to the batch method, the flow method has higher energy productivity and less waste emissions and is thus expected to be a sustainable manufacturing method that saves energy and reduces waste. In 2011, the U.S. Food and Drug Administration (FDA) proposed that the batch method should be replaced by the continuous flow method in the next 25 years.
(Flow Precision Synthesis Consortium).

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